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Membrane Target Systems: GABA B1a in HEK (human) membrane preparation, in HEK-293 cells. 400 Units.

Cell membranes prepared from HEK293 cells stably transfected with human GABA B1a receptor, 400 units.

Some of our receptors may be restricted for sale in specified countries. Please inquire.

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Overview

Membrane Target Systems are quality assured frozen membranes from cells that express recombinant or endogenous receptors.

We submit every batch of receptor to stringent quality control testing that includes saturation radioligand binding assay to determine receptor concentration (Bmax) and affinity (Kd). Competition binding assays are performed determine affinity (Ki) against known reference agonists and antagonists. GTP?S data is also provided for some of our Gi-coupled receptors.

Membranes are carefully prepared and ready for a variety of HTS applications, including radioligand binding (using either proximitymethods, such as FlashPlate, or classical filtration methods).

Products are packaged as frozen crude membrane preparations. One assay unit is defined as micrograms of protein, defined by competition binding assay (filtration). A complete product description and recommended protocol are included on the Product Information Sheet.

Some of our receptors may be restricted for sale in specified countries. Please inquire.

Specifications

Assay Target Class GPCR
Assay Target Type Membrane preparation
Assay Validated Binding
Host Cell HEK293
Product Brand Name Membrane Target Systems
Receptor Type GABA
Shipping Condition Dry Ice
Therapeutic Area Central Nervous System
Unit Size 400 units
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Radiometric Reagents Guide 2010-2011

For over 50 years PerkinElmer has been a leading supplier of radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments. Today is no different. We have always been committed to providing you products for all of your radiometric needs and we are still committed today.

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